Thursday, January 23, 2014

Mind-Blowing, Life-Saving Research  
Jackie Gingrich Cushman / Townhall Columnist
 
 
My mother's father died of cancer before I was born. My mother was pregnant with me, but had not told her father that she was to have a second child. The story I've been told is that they opened him up to remove the cancer -- and found it everywhere. They closed him back up and sent him home to die.

Both of my mother's brothers died of cancer. All three of these men were heavy smokers, one ignored the signs of potential trouble for years, and all three died from cancer.

My mother was diagnosed with cancer in 1978 and beat it. She was diagnosed a second time in 2005, but again beat cancer. She went to heaven last fall, but not due to cancer. She was not a smoker -- so what was the cause?

Her sister, my aunt, has never had cancer. I've often wondered, what genetics, lifestyles and triggers can make a difference in the cause of cancer?

There are some scientific discoveries so mind blowing that when you first hear about them you know that they are really, really big. That there will be ramifications for decades, even though you don't know what the ramifications will be.

The grandness of the discovery captures your imagination and changes your thoughts about relationships and life, even thought you don't quite understand the details, the underpinnings of the discovery.

Such is the discovery noted in The New York Times article this week, "Seeing X Chromosomes in a New Light," by Carl Zimmer. The article captured my imagination and broadened my mind.

The last time that I dealt with chromosomes was in college biology, when I had the mistaken belief that biology was my future and my major. A few chemistry labs later and one histology class, and I knew that my future was not in biology, but in business, where getting an A did not involve donning goggles and aprons for hours at a time.

As a quick review, the female chromosomes are XX and males are XY. Children receive one of their mother's X-chromosomes and either the X, or Y-chromosome from their father. The transmission of the father's chromosome determines whether the child is a male or female. This is not new news, but old.

Females, having two X-chromosomes, shut down one of the chromosomes at a cellular level. Which X-chromosome is shut down varies by cell -- in some it's the one passed down by the father, in others it's the chromosome that is passed down by the mother.

OK -- so scientists have known about this for over five decades, and it's just now coming to my attention -- but why the press now?

A recent study was published in "Neuron," that included maps of the X-chromosome inactivation.

"They found a remarkable complexity to the pattern in which the chromosomes were switched on and off," according to Zimmer.

Females have two copies of the X-chromosome, each of which has different versions of the genes not found on the other. This allows for one or the other to be used in the cell, leading to more genetic diversity than males. If one of the genes has a weakness -- the other can be used.

"Females simply have access to realms of biology that males do not have," Huntington Willard, the director of Duke University's institute of Genome Sciences & Policy noted.

The recent published research led by Dr. Nathans showed illuminated maps of where different X-chromosomes were activated in various cells within the bodies of mice. Nathans "speculates that using chromosomes from both parents is especially useful in the nervous system. It could create more ways to process information. 'Diversity in the brain is the name of the game.'"

What shuts down the second X-chromosome? It's a number of molecules, led by what has been named the Xist.

Dr. Lee, a Howard Hughes Medical Institute investigator at Harvard Medical School, has found that when the Xist is inactivated and the second X-chromosome is allowed to be active, it creates extra proteins. These extra proteins can drive a cell to grow uncontrollably. This additional uncontrollable growth makes cancer is more likely.

Women's brains are created differently, on the molecular, cellular level. What does this mean? I'm not sure, but I'm fascinated. Now that we know Xist exists, maybe we can determine how it becomes inactive -- and ensure it remains inactive.

To me, this new research is both mind-blowing and potentially life-saving.
Not so fast, Andrew Cuomo. We see what you did there. After publicly bashing conservative New Yorkers as "extreme" people who have no place in his state, the intolerant Democratic governor wants to blame the media for his unmistakable contempt for those who oppose abortion, support gun rights and defend traditional marriage. 

Newsflash: Crapweasel politicians can backtrack and scapegoat, but they can't hide.

When he railed against socially conservative Republican candidates in a radio interview last week, Cuomo hyperbolically singled out those he called "right-to-life, pro-assault-weapon, anti-gay" citizens. Sounding unapologetically purge-tastic, the governor said these political opponents "have no place in the state of New York, because that's not who New Yorkers are." His bigoted comments provoked a fierce social-media-driven backlash led by devout Catholics and Second Amendment activists in the Empire State. And now, he's got job-creating, tax-paying conservative business people threatening to leave. Heckuva job, Andy!

In a desperate damage control attempt, Cuomo issued a statement claiming that the New York Post "distorted" his words. It's always the messenger's fault. The Shove Guv also accused his critics of being "entirely reckless with facts and the truth." Really? There was no equivocation in Cuomo's political eviction wish. Whether he was talking about conservative candidates and/or the voters and donors who support them, you can't get any clearer than "have no place in the state of New York."

Translation: You don't belong. Pack your bags. Don't let the door hit ya on the way out. Scram.

All of his lefty friends on MSNBC and at Soros Central may be cheering Cuomo on, but this marginalization strategy is bound to backfire. Here in Colorado, supposedly moderate Democratic Gov. John Hickenlooper threw in with the radical gun-control crowd and is now paying the price. Major businesses have left the state. Two leading state Democratic legislators were recalled last fall by grassroots campaigns outspent 8-to-1 by gun-control forces underwritten by New York Nanny Stater Michael Bloomberg and Bill Gates.

Reminder: It wasn't just "extreme conservatives" who revolted. Pueblo Democrat Angela Giron lost in her Obama-loving Democratic Senate District 3 by a whopping 12 points.

Another state Democrat and staunch gun-control extremist, Evie Hudak, resigned in disgrace last November rather than face the wrath of the independent recallers. Once a hot 2016 Democratic presidential prospect, Hickenlooper's approval ratings have plunged.

Cuomo also has set himself up for an unforgettable schooling by hundreds of thousands of pro-lifers who are gathering in Washington, D.C., this week for the 41st annual March for Life. "I am guessing that Andrew Cuomo's remarks are going to be repeated by every speaker on the platform," Stasia Zoladz Vogel, president of the Buffalo Regional Right to Life Committee, predicted in the Buffalo News before the Wednesday march.

As for Cuomo's reckless dismissal of what he considers an "extreme" minority, a recent poll of New Yorkers showed that the vast majority "support sensible restrictions on abortions, with 80 percent opposing unlimited abortion through the ninth month of pregnancy and 75 percent opposing changes in current law so that someone other than a doctor can perform an abortion." Contrary to Cuomo's distorted view, the 21st-century pro-life movement is a diverse convergence of increasingly young and minority activists, feminist pro-lifers, independents and social conservatives. And contrary to Cuomo's reckless telling of history, pro-life activism is ingrained in New York history.

The suffragists who famously met at Seneca Falls, N.Y., were ardent advocates for life. They didn't mince words. Elizabeth Cady Stanton condemned the "murder of children, either before or after birth." Alice Paul, who crusaded for the Equal Rights Amendment, called abortion "the ultimate exploitation of women." Dr. Elizabeth Blackwell, as Susan B. Anthony List President Marjorie Dannenfelser pointed out in her review of pro-life feminism, was horrified by the abortion industry and the women who enabled it:

"The gross perversion and destruction of motherhood by the abortionist filled me with indignation, and awakened active antagonism. That the honorable term 'female physician' should be exclusively applied to those women who carried on this shocking trade seemed to me a horror. It was an utter degradation of what might and should become a noble position for women."

Now we know where Andrew Cuomo would have stood had he been around when pro-life suffragists came knocking on New York's doors: blocking their way.

Cuomo insists he "respects" all of the people he dumped on last week. Yet, he continues to willfully mischaracterize their positions and smear them as dangerous haters. It's telling that he employs the partisan pejorative labels "anti-gay" and "pro-assault weapon" alongside "right to life." As if endorsing the "right to life" is in itself an act of bigotry or a horrific, unspeakable crime.

There are no do-overs: Cuomo rolled out the unwelcome mat and announced a new state of intolerance. His undemocratic extremism is as extreme as it gets. Out: "I Love New York." In: "New York Hates You." Let the homebuyer, business owner, taxpayer, voter and visitor beware.

White House refuses to say whether billions it is giving Iran in unfrozen assets will be used to fund jihad terror

/ Jihad Watch
 

ayatollah-ali-khamenei.jpg?w=620Nothing has been done to stop this money being used in this way — so now the global jihad will be funded in part by your taxpayer dollars. Of course, this has already been the case in Libya and Syria. What fools these kuffar be!

“Iran Sanctions Relief Could Fund Terrorism Against U.S.,” by Adam Kredo for the Washington Free Beacon, January 21:
Iran has been granted absolute control over more than $4 billion that will be unfrozen and returned to Tehran under the recently enacted nuclear accord, causing concern that the cash will be used to fund terrorism.
The billions in cash come with no strings attached, meaning that Iran has complete authority over how the funds are spent—and the U.S. government cannot ensure that it will not go toward terrorism.
The White House did not mandate oversight of the funds under the nuclear deal, leading to concerns that one of the world’s top terrorism sponsors will give a cash infusion to radicals across the Middle East.
“Once the money is transferred to Iran we have no ability to determine how that money is allocated,” said Jonathan Schanzer, a former terrorism finance analyst at the Treasury Department, which is tasked with enforcing sanctions on Iran.
The U.S. State Department has designated Iran as the world’s “most active state sponsor of terrorism.”
“There is no guarantee this cash is going into some fund that will help Iran’s purported moderates,” Schanzer said. “This is going into the account of the Islamic Republic, which can be dispersed to a wide range of different actors, many of whom are bad.”
Iran’s elite Revolutionary Guard Corps (IRGC), for instance, has been known to wage clandestine terror operations across the globe and train radical forces.
Iran also is the principal backer of Hezbollah, which has long terrorized Israel and is currently operating on Tehran’s behest inside Syria to bolster embattled President Bashar al-Assad.
Other Iranian-backed militias have operated in Iraq and Afghanistan, where they have been known to carry out terror attacks against U.S. and Western forces.
“What has gone overlooked largely is that these funds could be handed to other bad actors that work for or on behalf of the Iranian regime,” Schanzer said.
Iranian funds have long been frozen in banks across the globe under strict sanctions imposed by the United States. As these sanctions are rolled back under the nuclear deal, the once frozen funds will be sent to the Central Bank of Iran (CBI).
Iran is set to repatriate more than $4 billion in the next several months as its accounts are unfrozen.
The White House is staying quiet on the issue.
When asked last week “what safeguards will be in place to make sure that money is not funneled to terror groups by Iran,” White House Press Secretary Jay Carney declined to answer….

FLORIDA: Black Republican under fire for saying Obama should be hanged for treason when convicted

From Bare Naked Islam 

 

Florida-House-candidate-Joshua-Black-President-Obama-should-hang-for-war-crimesA Republican candidate for the Florida House of Representatives is in hot water after he agreed Monday that President Barack Obama should be hanged for treason. Joshua Black, an African-American, agreed to the idea of hanging the president after a Twitter user sent him the following public message: “I’m past impeachment. It’s time to arrest and hang him high.” “Agreed,” Black tweeted in response.

 

The Blaze  (h/t Mike F)

black1

 

A Republican candidate for the Florida House in a nearby district, Chris Latvala, was quick to denounce Black.

“[Y]ou aren’t seriously calling for the killing of Obama are you?” Latvala asked, adding that Black is an “embarrassment.”

black2

 

Black remained defiant, explaining that Obama could only be executed after he has stood trial.

black31

black4

 

Black then took to Facebook to explain himself:

black5

 

It wasn’t long before the local GOP chairman, Michael Guju, Republican Gov. Rick Scott and others joined Latvala in calling on Black to abandon his bid for congress. “It is impossible to accept this statement,” Guju said. “This is wholly unacceptable and unduly provocative.” 


BhoGoesToJailvi-vi“Joshua Black’s comments on President Barack Obama are outrageous,” Gov. Scott tweeted Tuesday. “Floridians expect more from our leaders and he should immediately withdraw his candidacy to represent families of Pinellas County.” (Time for Allen West to replace Scott as Governor)

 

Black resigned Tuesday from a liaison position with the Pinellas County Republican Executive Committee, according to WTSP-TV. But he said he would not drop out of the race. (Good)

 

Black said Tuesday that he has been paid a visit by the United States Secret Service.


Op-ed: 
Stick and stones might break bones but big mouth Democratic governors do send people
packing 

By: Diane Sori  

By now we all know that last Friday in a radio interview, ubber liberal New York Governor Andrew Cuomo caused quite a stir when discussing the split in the Republican party...a split between the moderates... translation: the RINOS...and the true conservatives of the party who he accused of being anti-abortion, anti-gay rights, pro-assault weapons, and pro-Second Amendment...which by the way they are, but it's what Cuomo said after that has raised the ire of conservatives everywhere NOT just in New York.

Needing moderate RINO support and endorsements for his 2014 re-election bid, especially from those in big money Democratic electorates on Long Island and in Westchester county he asked, “Who are they?...Are they these extreme conservatives, who are right to life, pro-assault weapon, anti-gay? Is that who they are? Because if that is who they are and if they are extreme conservatives, they have no place in the state of New York.’’ 

And the fallout from his verbal diarrhea started almost immediately and damage control went into full operational mode. And true to Democratic form, Cuomo's people claimed in an open letter to the editor of the New York Post that his words were “distorted” and that Cuomo wasn't talking about individuals per se, but was talking about conservative candidates wanting to run in his state.

“It is clear that the governor was making the observation that an extreme right candidate cannot win statewide because this is a politically moderate state (either moderate Republican or moderate Democratic),” the letter stated.

Yeah right...for Cuomo's people took a page directly from the Obama playbook of NOT taking responsibility for what came out of one's own mouth...just like when Obama tried to claim that "If you like your insurance...if you like your doctor...you can keep them...period" was taken out of intended context...and did what was expected of them as they covered-up with lies Cuomo's words in an effort to divert and deflect the masses away from the vileness spewed by this angry, leftist-leaning, party-loyal, conservative hater.

And anyway NO matter how his people try to temper down the so-called 'intended meaning' of  Cuomo words, NO lies now said can cover for the fact that nowhere in Cuomo's statement is the word 'candidate' mentioned or even alluded to.

And as the initial the firestorm cleared, what remained from Cuomos's very own personal 'Bridgegate' is the question of why is he pushing so hard to win over the moderate (RINO) Republicans...simply, it's because he's losing support from the base...those wealthy big money left-wing progressives who are needed NOT just to finance his campaign...a campaign with a current war chest of 33 million dollars...but also to stir up the Democratic masses against any and all opposition. And the fact that he's already at odds with recently elected NYC Mayor Bill de Blasio, with State Attorney General Eric Schneiderman, with State Comptroller Tom DiNapoli, and with Assembly Speaker Sheldon Silver...does NOT bode well and can hurt his chances for re-election...for you NEVER want to alienate those high ranking officials within your own party NO matter the amount in your war chest.

In fact, Westchester County Executive Rob Astorino, who's considering a run for governor himself, said of Cuomo’s far left radical comments, “New York already leads the nation in chasing away its own citizens because of extraordinary high taxes, so does Cuomo really want to bully millions more away?’’

And how right he is for although New York is a blue state, the Republicans are in possession of great sums of money the state needs and collects in taxes...just ask those like Donald Trump who pay into the state coffers millions in taxes every year. But those are the very people leaving New York, in fact a 2012 Tax Foundation study found that over taxation was the cause of 3.4 million New Yorkers leaving the state over the past 10 years. And businesses are right behind in the exodus...to a tune of $46 billion in taxable income...because in addition to the burdensome taxes they're also over regulated to the hilt.

These stats alone will amaze you...New York has a top progressive income tax bracket of nearly 9%, with New York City itself adding on 3.5% in additional taxes...which newly elected far-left Mayor de Blasio wants to increase. Add to that a New York gift tax, a gasoline and cigarette tax, property taxes, and an estate tax that averages about 11%. And when you add to that county and city sales taxes that average between 7% and 8.9%, you can see why New York's loss is Florida's economic gain as most of those leaving are coming to Florida. Florida is known as being a business friendly state with right-to-work laws...and this is a biggie...Florida has NO income tax, NO estate tax, and NO inheritance tax, and as an added bonus our local governments cannot impose any such levies as per Florida State Statutes.

And New Yorkers are leaving because of the game playing done by people like Governor Cuomo... true Democratic politician that he is...a man who puts party politics before the needs and wants of the people who elected him. Case in point...Cuomo, just like Obama, vetoes measures that pass both Houses if they do NOT conform to his personal views and party platform. And New Yorkers, just like many across the country, are plain sick and tired of this partisan nonsense with decisions made to benefit 'the party' alone. And last year to prove this point, Cuomo vetoed 82 House passed bills..and NO great surprise here...the vast majority were bills proposed by Republicans...like the one which providing a disability benefit to sheriffs, deputy sheriffs, and correction officers if they become physically or mentally incapacitated as a result of the actions by a civilian at a local jail or other county institution.  Cuomo couldn't wait to put his veto on that one.

And so while NY State Republican Party Chairman Ed Cox is calling for Cuomo to apologize, "I call upon Governor Cuomo to apologize to New York's good conservatives and Catholics for his statement that they 'have no place in the State of New York' and to all New Yorkers for poisoning New York's politics with divisive rhetoric at a time when New York needs to be united to address its continuing economic problems"...apologizes issued just to placate the politicians and sooth the hurt feelings of the masses amounts to just empty words.

And if truth be told, the only thing that can throw a wrench into the leftist agenda and hit them where it counts...in the pocketbook and state coffers...is what New Yorkers like FOX News conservative pundit Sean Hannity said and what a lot of everyday conservative New Yorkers are now feeling, "I'm not welcome in my own home state...that's fine. Governor Cuomo, I'm going to leave and I'm taking all of my money with me — every single solitary penny."

And to that I say, "Sean, you're welcome in Florida anytime."